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Programme

Semaine Mer. 29 Jeu. 30 Ven. 31 Liste

	Mer. 29	Jeu. 30	Ven. 31
08:00 09:00 10:00 11:00 12:00 13:00 14:00 15:00 16:00 17:00 18:00 19:00 20:00	Accueil et Déjeuner 12:30 - 14:30 (2h) Accueil et Déjeuner Workshop 14:30 - 17:00 (2h30) Workshop › New imaging tools for cellular cerebral studies - Nadja Van Camp, Molecular Imaging Research Center 14:30-15:00 (30min) › Contribution of PET/SPECT functional imaging in Parkinson's disease (PD) - Sonia Lavisse, Molecular Imaging Research Centre (MIRCen) 15:00-15:30 (30min) › Preclinical MR biomarkers in Parkinson's disease models - Alexandra Petiet, Institut du Cerveau et de la Moëlle Epinière 15:30-16:00 (30min) › IPSCs and Microfluidics for the study of Parkinson's Disease - Anselme Perrier, Laboratoire des Maladies Neurodégénératives, MIRCen 16:00-17:00 (1h) Visite de l'ICM 17:00 - 18:00 (1h) Visite de l'ICM Alexandra Petiet, Olga Corti Cocktail ouvert à tous les participants au congrès 18:00 - 19:00 (1h) Cocktail ouvert à tous les participants au congrès	Accueil des participants 8:00 - 8:30 (30min) Accueil des participants Inscriptions et café Introduction 8:30 - 9:00 (30min) Introduction Session 1 : Analyses génomiques - Génétique et Transcriptomique 9:00 - 10:40 (1h40) Session 1 : Analyses génomiques - Génétique et Transcriptomique Olga Corti, Marie-Christine Chartier-Harlin › An update on the Genetics of Parkinson's disease - Vincenzo Bonifati, Erasmus University Medical Center, Rotterdam 09:00-09:30 (30min) › GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study - Agustin Ruiz, Fundacio ACE [Barcelona] 09:30-10:00 (30min) › Transcriptomic signatures of brain regional vulnerability to Parkinson's disease - Arlin Keo, Delft Bioinformatics Lab, Delft University of Technology [Delft], Leiden Computational Biology Center, Leiden University Medical Center 10:00-10:30 (30min) › Mitochondrial dysfunctions caused by neuron-related RNA binding protein misexpression - Stylianos Ravanidis, Basic Sciences Division I, Biomedical Research Foundation, Academy of Athens, 11527 Athens 10:30-10:35 (05min) › Deciphering the cellular and molecular response of human dopaminergic neurons to mitochondrial stress - Jana Heneine, Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute 10:35-10:40 (05min) Pause café 10:40 - 11:00 (20min) Pause café Session 2 : Avancées récentes en Imagerie 11:00 - 12:40 (1h40) Session 2 : Avancées récentes en Imagerie Emmanuel Brouillet, Nadja Van Camp › Can we use brain connectivity to improve individual patient DBS outcomes? - Brian Lau, Institut du Cerveau et de la Moelle épinière 11:00-11:30 (30min) › Multimodal MRI in Parkinson's disease and parkinsonian syndromes - Patrice Péran - Toulouse NeuroImaging Centre (ToNIC) 11:30-12:00 (30min) › Pathophysiology of dyskinesia and behavioral disorders in non-human primates: Insights from multimodal imaging - Véronique Sgambato - Institut des Sciences Cognitives Marc Jeannerod, Bron 12:00-12:30 (30min) › Evaluation of dopaminergic neuronal loss and synaptic changes in an α-synuclein overexpressing model of PD - Pauline Roost, CNRS, UMR9199, CEA, DRF, IBFJ, MIRCen 12:30-12:35 (05min) Déjeuner et Posters 12:40 - 14:00 (1h20) Déjeuner et Posters Session 3 : Qu'apprenons-nous des inclusions d'a-synucléine ? 14:00 - 15:40 (1h40) Session 3 : Qu'apprenons-nous des inclusions d'a-synucléine ? Vincenzo Bonifati, Luc Bousset › Neuropathology of Parkinson' s disease and dementia of Lewy Bodies. - Charles Duyckaerts, Département de Neuropathologie Raymond Escourolle, Groupe Hospitalier Universitaire Pitié-Salpêtrière 14:00-14:30 (30min) › Neuronal Parkinson inclusions are different than expected - Henning Stahlberg, Center for Cellular Imaging and Nanoanalytics (C-CINA) 14:30-15:00 (30min) › 3D structure determination of amyloid fibrils using solid-state NMR spectroscopy. - 15:00-15:30 (30min) › Alpha-synuclein conformational strains spread, seed and target neuronal cells differentially after injection into the olfactory bulb - Nolwen Rey, MIRCen, CEA & CNRS UMR 9199, Fontenay-aux-Roses 15:30-15:35 (05min) › GCI-induced neurodegeneration and synucleinopathy in non-human primates - Margaux Teil, Institut des Maladies Neurodégénératives [Bordeaux] 15:35-15:40 (05min) Pause café 15:40 - 16:00 (20min) Pause café Session 4 : Localisation et régulation de l'a-synucléine 16:00 - 17:40 (1h40) Session 4 : Localisation et régulation de l'a-synucléine Sabine Hilfiker, Stéphane Hunot › Alpha-synuclein: a troublesome traveller - Donato Di Monte, German Research Center for Neurodegenerative Diseases - Deutsches Zentrum für Neurodegenerative Erkrankungen 16:00-16:30 (30min) › Posttranslational modifications: modulators of alpha-synuclein biology and pathobiology - Tiago Fleming Outeiro - University Medical Center Goettingen 16:30-17:00 (30min) › Transcriptional regulation of alpha-synuclein by the TRIM17-TRIM41-ZSCAN21 pathway - Solange Desagher, Institute of Molecular Genetics of Montpellier, UMR 5535 CNRS-Université de Montpellier 17:00-17:30 (30min) › Characterising the role of alpha synuclein in Ferroptosis in the context go Parkinson's disease - Laura Mahoney Sanchez, University and University Hospital of Lille, INSERM UMRS_1171, LICEND COEN Center 17:30-17:35 (05min) › Identification of targets and markers of Parkinson's disease-associated neuroinflammation - Cansu YILDIRIM, Brain and Spine Institute (ICM) 17:35-17:40 (05min) Pause 17:40 - 18:00 (20min) Pause Session 5 : Patients & associations 18:00 - 20:00 (2h) Session 5 : Patients & associations Emmanuel Brouillet, Marie-Christine Chartier-Harlin › Association France Parkinson - Marie Fuzzati, Guy Janet Maitre - Association France Parkinson 18:00-18:20 (20min) › Fondation Vaincre Alzheimer - Maï Panchal, Directrice Scientifique de la Fondation Vaincre Alzheimer 18:20-18:30 (10min) › Brain biobanking - Charles Duyckaerts, Département de Neuropathologie Raymond Escourolle, Groupe Hospitalier Universitaire Pitié-Salpêtrière 18:30-18:40 (10min) › Conférence plénière ouverte au public : La chirurgie dans la maladie de Parkinson, état de l'art et perspectives - Stéphane PALFI, CHU Henri Mondor, Créteil 18:45-19:45 (1h)	Accueil des participants 8:30 - 9:00 (30min) Accueil des participants Café Session 6 : modélisation moléculaire utilisant d'autres gènes 9:00 - 10:40 (1h40) Session 6 : modélisation moléculaire utilisant d'autres gènes Tiago Outeiro, Cristine Alves Da Costa › The role of Lipid Droplets in Parkinson's Disease - Bertrand Mollereau, Laboratoire de Biologie Moléculaire de la Cellule, Lyon 09:00-09:30 (30min) › Mitochondrial functions of PINK1 - Vanessa Morais, Instituto de Medicina Molecular (iMM) Lisboa 09:30-10:00 (30min) › Cellular mechanisms underlying LRRK2-related Parkinson´s disease - Sabine Hilfiker, Rutgers University, New Jersey Medical School 10:00-10:30 (30min) › Triallelic stem cell model of Parkinson's disease reveals epistatic interaction between PRKN and GBA - Zoé Hanss, Luxembourg Centre For Systems Biomedicine 10:30-10:35 (05min) › LRRK2 interacts with a subset of endosomal vesicular SNAREs: potential role in the physiopathology of Parkinson Disease - Francesca Filippini, Institut de Psychiatrie et Neuroscience de Paris 10:35-10:40 (05min) Pause café 10:40 - 11:00 (20min) Pause café Session 7 : Développements précliniques et translationnels 11:00 - 12:40 (1h40) Session 7 : Développements précliniques et translationnels Emmanuel Brouillet, Erwan Bézard › Impulse control disorders and levodopa-induced dyskinesias in Parkinson's disease - Pierre-Olivier Fernagut, Laboratoire de Neurosciences Expérimentales et Cliniques, Poitiers 11:00-11:30 (30min) › From bench to bedside in a peculiar synucleopathy: the multiple system atrophy - Wassilios Meissner, Institut des Maladies Neurodégénératives, Bordeaux 11:30-12:00 (30min) › A brain-spine interface alleviating gait deficits in a primate model of parkinson's disease - Jocelyne Bloch-Pasche, Centre Hospitalier Universitaire Vaudois, Lausanne 12:00-12:30 (30min) › Acidic nanoparticles prevent neurodegeneration in LB-induced Parkinson's disease mouse model - Marie-Laure AROTCARENA, Institut des Maladies Neurodégénératives [Bordeaux] 12:30-12:35 (05min) › Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson's disease - Sébastien BROT, Laboratoire de neurosciences expérimentales et cliniques 12:35-12:40 (05min) Déjeuner - Posters 12:40 - 14:00 (1h20) Déjeuner - Posters Axion BioSystems, sponsor de HOPE 2020 14:00 - 14:30 (30min) Axion BioSystems, sponsor de HOPE 2020 Giovanna De Filippi Session 8 : de la cellule unique aux modèles 3D (1) 14:30 - 15:40 (1h10) Session 8 : de la cellule unique aux modèles 3D (1) Richard Wade-Martins, Anselme Perrier › Cellular Brain Repair for Parkinson's Disease: Is the Answer in the (Biomaterial) Matrix? - Eilis Dowd, Pharmacology & Therapeutics, National University of Ireland, Galway, Ireland 14:30-15:00 (30min) › iPSC neuronal models of Parkinson's: from pathological mechanisms to target discovery - Richard Wade-Martins - Oxford Parkinson's Disease Centre - Department of Physiology, Anatomy and Genetics, University of Oxford 15:00-15:30 (30min) › Specific vulnerability of neuronal populations & Transfer of alpha-synuclein in reconstructed neural networks - Josquin Courte, Physico-Chimie-Curie, Neuroscience Paris Seine 15:30-15:35 (05min) Pause café 15:40 - 16:00 (20min) Pause café Session 8 : de la cellule unique aux modèles 3D (2) 16:00 - 17:00 (1h) Session 8 : de la cellule unique aux modèles 3D (2) Eilis Dowd, Anselme Perrier › New insights into the complex role of mitochondria in Parkinson's disease - Anne Grünewald, Luxembourg Centre for Systems Biomedicine 16:00-16:30 (30min) › 3D Cultures of Parkinson's Disease‐Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing - Jens Christian Schwamborn, Luxembourg Centre for Systems Biomedicine 16:30-17:00 (30min) Remise des prix et conclusion 17:00 - 18:00 (1h) Remise des prix et conclusion

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