Programme

mercredi 29 janvier 2020

Heures événement (+)
12:30 - 14:30 Accueil et Déjeuner  
14:30 - 17:00 Workshop (+)  
14:30 - 15:00 › New imaging tools for cellular cerebral studies - Nadja Van Camp, Molecular Imaging Research Center  
15:00 - 15:30 › Contribution of PET/SPECT functional imaging in Parkinson's disease (PD) - Sonia Lavisse, Molecular Imaging Research Centre (MIRCen)  
15:30 - 16:00 › Preclinical MR biomarkers in Parkinson's disease models - Alexandra Petiet, Institut du Cerveau et de la Moëlle Epinière  
16:00 - 17:00 › IPSCs and Microfluidics for the study of Parkinson's Disease - Anselme Perrier, Laboratoire des Maladies Neurodégénératives, MIRCen  
17:00 - 18:00 Visite de l'ICM - Alexandra Petiet, Olga Corti  
18:00 - 19:00 Cocktail ouvert à tous les participants au congrès  

jeudi 30 janvier 2020

Heures événement (+)
08:00 - 08:30 Accueil des participants - Inscriptions et café  
08:30 - 09:00 Introduction  
09:00 - 10:40 Session 1 : Analyses génomiques - Génétique et Transcriptomique - Olga Corti, Marie-Christine Chartier-Harlin (+)  
09:00 - 09:30 › An update on the Genetics of Parkinson's disease - Vincenzo Bonifati, Erasmus University Medical Center, Rotterdam  
09:30 - 10:00 › GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study - Agustin Ruiz, Fundacio ACE [Barcelona]  
10:00 - 10:30 › Transcriptomic signatures of brain regional vulnerability to Parkinson's disease - Arlin Keo, Delft Bioinformatics Lab, Delft University of Technology [Delft], Leiden Computational Biology Center, Leiden University Medical Center  
10:30 - 10:35 › Mitochondrial dysfunctions caused by neuron-related RNA binding protein misexpression - Stylianos Ravanidis, Basic Sciences Division I, Biomedical Research Foundation, Academy of Athens, 11527 Athens  
10:35 - 10:40 › Deciphering the cellular and molecular response of human dopaminergic neurons to mitochondrial stress - Jana Heneine, Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute  
10:40 - 11:00 Pause café  
11:00 - 12:40 Session 2 : Avancées récentes en Imagerie - Emmanuel Brouillet, Nadja Van Camp (+)  
11:00 - 11:30 › Can we use brain connectivity to improve individual patient DBS outcomes? - Brian Lau, Institut du Cerveau et de la Moelle épinière  
11:30 - 12:00 › Multimodal MRI in Parkinson's disease and parkinsonian syndromes - Patrice Péran - Toulouse NeuroImaging Centre (ToNIC)  
12:00 - 12:30 › Pathophysiology of dyskinesia and behavioral disorders in non-human primates: Insights from multimodal imaging - Véronique Sgambato - Institut des Sciences Cognitives Marc Jeannerod, Bron  
12:30 - 12:35 › Evaluation of dopaminergic neuronal loss and synaptic changes in an α-synuclein overexpressing model of PD - Pauline Roost, CNRS, UMR9199, CEA, DRF, IBFJ, MIRCen  
12:40 - 14:00 Déjeuner et Posters  
14:00 - 15:40 Session 3 : Qu'apprenons-nous des inclusions d'a-synucléine ? - Vincenzo Bonifati, Luc Bousset (+)  
14:00 - 14:30 › Neuropathology of Parkinson' s disease and dementia of Lewy Bodies. - Charles Duyckaerts, Département de Neuropathologie Raymond Escourolle, Groupe Hospitalier Universitaire Pitié-Salpêtrière  
14:30 - 15:00 › Neuronal Parkinson inclusions are different than expected - Henning Stahlberg, Center for Cellular Imaging and Nanoanalytics (C-CINA)  
15:00 - 15:30 › 3D structure determination of amyloid fibrils using solid-state NMR spectroscopy. - Antoine Loquet - Chimie et Biologie des Membranes et des Nanoobjets  
15:30 - 15:35 › Alpha-synuclein conformational strains spread, seed and target neuronal cells differentially after injection into the olfactory bulb - Nolwen Rey, MIRCen, CEA & CNRS UMR 9199, Fontenay-aux-Roses  
15:35 - 15:40 › GCI-induced neurodegeneration and synucleinopathy in non-human primates - Margaux Teil, Institut des Maladies Neurodégénératives [Bordeaux]  
15:40 - 16:00 Pause café  
16:00 - 17:40 Session 4 : Localisation et régulation de l'a-synucléine - Sabine Hilfiker, Stéphane Hunot (+)  
16:00 - 16:30 › Alpha-synuclein: a troublesome traveller - Donato Di Monte, German Research Center for Neurodegenerative Diseases - Deutsches Zentrum für Neurodegenerative Erkrankungen  
16:30 - 17:00 › Posttranslational modifications: modulators of alpha-synuclein biology and pathobiology - Tiago Fleming Outeiro - University Medical Center Goettingen  
17:00 - 17:30 › Transcriptional regulation of alpha-synuclein by the TRIM17-TRIM41-ZSCAN21 pathway - Solange Desagher, Institute of Molecular Genetics of Montpellier, UMR 5535 CNRS-Université de Montpellier  
17:30 - 17:35 › Characterising the role of alpha synuclein in Ferroptosis in the context go Parkinson's disease - Laura Mahoney Sanchez, University and University Hospital of Lille, INSERM UMRS_1171, LICEND COEN Center  
17:35 - 17:40 › Identification of targets and markers of Parkinson's disease-associated neuroinflammation - Cansu YILDIRIM, Brain and Spine Institute (ICM)  
17:40 - 18:00 Pause  
18:00 - 20:00 Session 5 : Patients & associations - Emmanuel Brouillet, Marie-Christine Chartier-Harlin (+)  
18:00 - 18:20 › Association France Parkinson - Marie Fuzzati, Guy Janet Maitre - Association France Parkinson  
18:20 - 18:30 › Fondation Vaincre Alzheimer - Maï Panchal, Directrice Scientifique de la Fondation Vaincre Alzheimer  
18:30 - 18:40 › Brain biobanking - Charles Duyckaerts, Département de Neuropathologie Raymond Escourolle, Groupe Hospitalier Universitaire Pitié-Salpêtrière  
18:45 - 19:45 › Conférence plénière ouverte au public : La chirurgie dans la maladie de Parkinson, état de l'art et perspectives - Stéphane PALFI, CHU Henri Mondor, Créteil  

vendredi 31 janvier 2020

Heures événement (+)
08:30 - 09:00 Accueil des participants - Café  
09:00 - 10:40 Session 6 : modélisation moléculaire utilisant d'autres gènes - Tiago Outeiro, Cristine Alves Da Costa (+)  
09:00 - 09:30 › The role of Lipid Droplets in Parkinson's Disease - Bertrand Mollereau, Laboratoire de Biologie Moléculaire de la Cellule, Lyon  
09:30 - 10:00 › Mitochondrial functions of PINK1 - Vanessa Morais, Instituto de Medicina Molecular (iMM) Lisboa  
10:00 - 10:30 › Cellular mechanisms underlying LRRK2-related Parkinson´s disease - Sabine Hilfiker, Rutgers University, New Jersey Medical School  
10:30 - 10:35 › Triallelic stem cell model of Parkinson's disease reveals epistatic interaction between PRKN and GBA - Zoé Hanss, Luxembourg Centre For Systems Biomedicine  
10:35 - 10:40 › LRRK2 interacts with a subset of endosomal vesicular SNAREs: potential role in the physiopathology of Parkinson Disease - Francesca Filippini, Institut de Psychiatrie et Neuroscience de Paris  
10:40 - 11:00 Pause café  
11:00 - 12:40 Session 7 : Développements précliniques et translationnels - Emmanuel Brouillet, Erwan Bézard (+)  
11:00 - 11:30 › Impulse control disorders and levodopa-induced dyskinesias in Parkinson's disease - Pierre-Olivier Fernagut, Laboratoire de Neurosciences Expérimentales et Cliniques, Poitiers  
11:30 - 12:00 › From bench to bedside in a peculiar synucleopathy: the multiple system atrophy - Wassilios Meissner, Institut des Maladies Neurodégénératives, Bordeaux  
12:00 - 12:30 › A brain-spine interface alleviating gait deficits in a primate model of parkinson's disease - Jocelyne Bloch-Pasche, Centre Hospitalier Universitaire Vaudois, Lausanne  
12:30 - 12:35 › Acidic nanoparticles prevent neurodegeneration in LB-induced Parkinson's disease mouse model - Marie-Laure AROTCARENA, Institut des Maladies Neurodégénératives [Bordeaux]  
12:35 - 12:40 › Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson's disease - Sébastien BROT, Laboratoire de neurosciences expérimentales et cliniques  
12:40 - 14:00 Déjeuner - Posters  
14:00 - 14:30 Axion BioSystems, sponsor de HOPE 2020 - Giovanna De Filippi  
14:30 - 15:40 Session 8 : de la cellule unique aux modèles 3D (1) - Richard Wade-Martins, Anselme Perrier (+)  
14:30 - 15:00 › Cellular Brain Repair for Parkinson's Disease: Is the Answer in the (Biomaterial) Matrix? - Eilis Dowd, Pharmacology & Therapeutics, National University of Ireland, Galway, Ireland  
15:00 - 15:30 › iPSC neuronal models of Parkinson's: from pathological mechanisms to target discovery - Richard Wade-Martins - Oxford Parkinson's Disease Centre - Department of Physiology, Anatomy and Genetics, University of Oxford  
15:30 - 15:35 › Specific vulnerability of neuronal populations & Transfer of alpha-synuclein in reconstructed neural networks - Josquin Courte, Physico-Chimie-Curie, Neuroscience Paris Seine  
15:40 - 16:00 Pause café  
16:00 - 17:00 Session 8 : de la cellule unique aux modèles 3D (2) - Eilis Dowd, Anselme Perrier (+)  
16:00 - 16:30 › New insights into the complex role of mitochondria in Parkinson's disease - Anne Grünewald, Luxembourg Centre for Systems Biomedicine  
16:30 - 17:00 › 3D Cultures of Parkinson's Disease‐Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing - Jens Christian Schwamborn, Luxembourg Centre for Systems Biomedicine  
17:00 - 18:00 Remise des prix et conclusion  
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